beta Amyloid antibody (AA 631-680)
Quick Overview for beta Amyloid antibody (AA 631-680) (ABIN4900975)
Target
See all beta Amyloid (Abeta) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 631-680
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Purpose
- Rabbit polyclonal to Amyloid-β.
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Specificity
- Amyloid-β Polyclonal Antibody detects endogenous levels of Amyloid-β
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Characteristics
- Rabbit Polyclonal to Amyloid-β.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from Amyloid-beta
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Isotype
- IgG
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Application Notes
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WB 1:500-2000
ELISA 1:10000-20000 -
Comment
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Expressed in all fetal tissues examined with highest levels in brain, kidney, heart and spleen. Weak expression in liver. In adult brain, highest expression found in the frontal lobe of the cortex and in the anterior perisylvian cortex-opercular gyri. Moderate expression in the cerebellar cortex, the posterior perisylvian cortex-opercular gyri and the temporal associated cortex. Weak expression found in the striate, extra-striate and motor cortices. Expressed in cerebrospinal fluid, and plasma. Isoform APP695 is the predominant form in neuronal tissue, isoform APP751 and isoform APP770 are widely expressed in non-neuronal cells. Isoform APP751 is the most abundant form in T-lymphocytes. Appican is expressed in astrocytes.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- beta Amyloid (Abeta) (Amyloid beta (Abeta))
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Alternative Name
- Amyloid-beta
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Gene ID
- 351
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UniProt
- P05067
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Pathways
- Inflammasome
Target
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