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FGF6 antibody

FGF6 Reactivity: Human WB, ELISA, Neut, Func Host: Goat Polyclonal unconjugated
Catalog No. ABIN490848
  • Target See all FGF6 Antibodies
    FGF6 (Fibroblast Growth Factor 6 (FGF6))
    Reactivity
    • 32
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 31
    • 3
    • 1
    Goat
    Clonality
    • 32
    • 3
    Polyclonal
    Conjugate
    • 16
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGF6 antibody is un-conjugated
    Application
    • 34
    • 13
    • 13
    • 11
    • 10
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Neutralization (Neut), Functional Studies (Func)
    Specificity
    Recognizes human, recombinant Fibroblast Growth Factor 6 (FGF6). ~50 % cross-reactivity with rhFGF4, less than 5 % cross-reactivity with rhFGF9 and less than 2 % cross-reactivity with FGF-acidic, rhFGF5 and rhFGF7. In direct ELISA, this antibody shows no cross-reactivity with other cytokines tested.
    Purification
    Immunoaffinity purified
    Immunogen
    Human, recombinant Fibroblast Growth Factor 6 (FGF6) from E. coli.

    Type of Immunogen: Recombinant protein
    Isotype
    IgG
    Top Product
    Discover our top product FGF6 Primary Antibody
  • Application Notes
    Approved: ELISA (0.5 - 1 μg/mL), Func, Neut, WB (0.1 - 0.2 μg/mL)

    Usage: Suitable for use in Neutralization, Western Blot and ELISA. Neutralization: ND50 is ~0.025-0.075 μg/mL in the presence of 1 ng/mL of rhFGF6 and 1 μg/mL of heparin, using the FGF6 responsive NR6R-3T3 fibroblasts as target cells. The Neutralization Dose50 (ND50) for this antibody is defined as that concentration of antibody required to yield one-half maximal inhibition of the cytokine activity on a responsive cell line, when that cytokine is present at a concentration just high enough to elicit a maximum response. Western Blot: 0.1-0.2 μg/mL with the appropriate secondary reagents to detect human FGF6. The detection limit for rhFGF6 is approximately 2 ng/lane under non-reducing and reducing conditions. ELISA: 0.5-1 μg/mL with the appropriate secondary reagents to detect human FGF6. The detection limit for rhFGF6 is ~0.16 ng/well.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS,  pH 7.2, 40 % glycerol.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target
    FGF6 (Fibroblast Growth Factor 6 (FGF6))
    Alternative Name
    FGF6 (FGF6 Products)
    Synonyms
    FGF6 antibody, hst2 antibody, fgf-6 antibody, hbgf-6 antibody, HBGF-6 antibody, HST2 antibody, Fgf-6 antibody, HSTF-2 antibody, fgf4 antibody, fgf6 antibody, fibroblast growth factor 6 antibody, fibroblast growth factor 6a antibody, FGF6 antibody, fgf6 antibody, Fgf6 antibody, fgf6a antibody
    Background
    Name/Gene ID: FGF6
    Family: HBGF

    Synonyms: FGF6, FGF-6, Fibroblast growth factor 6, HSTF-2, HBGF-6, HST-2, HST2, HSTF2
    Gene ID
    2251
    UniProt
    P10767
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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