Nitrotyrosine antibody (PE)

Catalog No. ABIN4912391

The Rabbit Polyclonal anti-Nitrotyrosine antibody is suitable to detect Nitrotyrosine in samples from Human, Mouse and Rat. It has been validated for WB and FACS.

Quick Overview for Nitrotyrosine antibody (PE) (ABIN4912391)

Target: Nitrotyrosine

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nitrotyrosine antibody is conjugated to PE

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-Nitrotyrosine Antibody (PE)

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Nitrotyrosine

Purification: Purified by Protein A.

Immunogen: KLH conjugated to Nitrotyrosine

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Nitrotyrosine

Target: Nitrotyrosine

Target Type: Chemical

Background:

Synonyms: NULL

Background: Nitrotyrosine is a marker for inflammation and nitric oxide (NO) production and is formed in the presence of the active metabolite NO. Because nitrotyrosine is a stable product of multiple pathways, such as the formation of peroxynitrite, its plasma concentration may be a useful determinant of NO-dependent damage in vivo. Nitrotyrosine has been detected in inflammatory processes such as septic shock, rheumatoid arthritis, celiac disease, atherosclerotic plaques and chronic renal failure.