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PPARA antibody

PPARA Reactivity: Human, Mouse WB Host: Mouse Monoclonal 7G5 unconjugated
Catalog No. ABIN4913181
  • Target See all PPARA Antibodies
    PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
    Reactivity
    • 98
    • 90
    • 67
    • 18
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 102
    • 12
    Mouse
    Clonality
    • 104
    • 10
    Monoclonal
    Conjugate
    • 49
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPARA antibody is un-conjugated
    Application
    • 100
    • 46
    • 40
    • 39
    • 39
    • 17
    • 14
    • 13
    • 9
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human, Mouse
    Purification
    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This PPARA antibody is generated from a mouse immunized with a recombination protein from the human region of human PPARA.
    Clone
    7G5
    Isotype
    IgG1
    Top Product
    Discover our top product PPARA Primary Antibody
  • Application Notes
    WB 1:300-5000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
    Alternative Name
    PPARA (PPARA Products)
    Synonyms
    NR1C1 antibody, PPAR antibody, PPARalpha antibody, hPPAR antibody, LOC100136415 antibody, PPARALPHA antibody, nr1c1 antibody, xPPARalpha antibody, xppara antibody, 4933429D07Rik antibody, AW742785 antibody, Nr1c1 antibody, PPAR-alpha antibody, Ppar antibody, peroxisome proliferator activated receptor alpha antibody, peroxisome proliferator-activated receptor alpha antibody, peroxisome proliferator activated receptor alpha L homeolog antibody, PPARA antibody, LOC100136415 antibody, ppara.L antibody, Ppara antibody, ppara antibody
    Background

    Synonyms: PPAR, NR1C1, hPPAR, PPARalpha, Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, PPARA

    Background: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.

    Gene ID
    5465
    UniProt
    Q07869
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
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