Tyrosine Hydroxylase antibody (AA 115-160) (PE)

Catalog No. ABIN4914980

The Rabbit Polyclonal anti-Tyrosine Hydroxylase antibody has been validated for WB. It is suitable to detect Tyrosine Hydroxylase in samples from Human, Rat and Mouse.

Quick Overview for Tyrosine Hydroxylase antibody (AA 115-160) (PE) (ABIN4914980)

Target: Tyrosine Hydroxylase (TH)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tyrosine Hydroxylase antibody is conjugated to PE

Application: Western Blotting (WB)

Product Details anti-Tyrosine Hydroxylase Antibody (PE)

Binding Specificity: AA 115-160

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Tyrosine Hydroxylase

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Tyrosine Hydroxylase

Target: Tyrosine Hydroxylase (TH)

Alternative Name: Tyrosine Hydroxylase

Background:

Synonyms: TYH, DYT14, DYT5b, Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH

Background: Neuronal Marker Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.

Gene ID: 7054

UniProt: P07101

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour