VWF antibody (AA 1815-1939)

Catalog No. ABIN4949944

The Mouse Monoclonal anti-VWF antibody is suitable to detect VWF in samples from Human. It has been validated for ELISA and IHC (p).

Quick Overview for VWF antibody (AA 1815-1939) (ABIN4949944)

Target: VWF (Von Willebrand Factor (VWF))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VWF antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: VWF-1767

Product Details anti-VWF Antibody

Binding Specificity: AA 1815-1939

Purpose: vWF Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Amino acids 1815-1939 from the human protein were used as the immunogen for this vWF antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: The optimal dilution of the vWF antibody for each application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the vWF antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for VWF

Target: VWF (Von Willebrand Factor (VWF))

Alternative Name: vWF

Background: Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

UniProt: P04275