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CD14 antibody (AA 292-322)

This anti-CD14 antibody is a Rabbit Polyclonal antibody detecting CD14 in FACS, WB, IHC and ELISA. Suitable for Human.
Catalog No. ABIN3030357

Quick Overview for CD14 antibody (AA 292-322) (ABIN3030357)

Target

See all CD14 Antibodies
CD14

Reactivity

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  • 36
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Human

Host

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Rabbit

Clonality

  • 297
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Polyclonal

Conjugate

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This CD14 antibody is un-conjugated

Application

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Binding Specificity

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    AA 292-322

    Purification

    Purified

    Immunogen

    A portion of amino acids 292-322 from the human protein was used as the immunogen for this CD14 antibody.

    Isotype

    Ig Fraction
  • Application Notes

    The stated application concentrations are suggested starting amounts. Titration of the CD14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at 4°C for up to one month. For long term, aliquot the CD14 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    CD14

    Alternative Name

    CD14

    Background

    In concert with LBP, CD14 binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. [UniProt]

    UniProt

    P08571

    Pathways

    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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