MECP2 antibody (AA 399-428)

Catalog No. ABIN3031769

The Rabbit Polyclonal anti-MECP2 antibody is suitable to detect MECP2 in samples from Human. It has been validated for WB, ELISA and FACS.

Quick Overview for MECP2 antibody (AA 399-428) (ABIN3031769)

Target: MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MECP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-MECP2 Antibody

Binding Specificity: AA 399-428

Purpose: MeCP2 Antibody

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Purified

Immunogen: A portion of amino acids 399-428 from the macfa protein was used as the immunogen for this MeCP2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the MeCP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4oC for up to one month. For long term, aliquot the MeCP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MECP2

Target: MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Alternative Name: MeCP2

Background: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. [RefSeq].

UniProt: Q95LG8

Pathways: Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane