NLRP12 antibody

Catalog No. ABIN3032018

Product Details anti-NLRP12 Antibody

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This NLRP12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Purified

Immunogen: This NALP12 antibody was produced from a mouse immunized with NLRP12/NALP12 recombinant protein.

Clone: 228CT4-1-3

Isotype: IgM kappa

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the NALP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500-1:1500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C for up to one month. For long term, aliquot the NALP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for NLRP12

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Alternative Name: NALP12 (NLRP12) (NLRP12 Products)

Synonyms: Nalp12 antibody, NALP12 antibody, CLR19.3 antibody, FCAS2 antibody, PAN6 antibody, PYPAF7 antibody, RNO antibody, RNO2 antibody, NLR family, pyrin domain containing 12 antibody, NLR family pyrin domain containing 12 antibody, NACHT, LRR and PYD domains-containing protein 3 antibody, Nlrp12 antibody, NLRP12 antibody, LOC100018508 antibody

Background: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome