ADA antibody (AA 287-314)

Catalog No. ABIN3029872

This Mouse Monoclonal antibody specifically detects ADA in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ADA antibody (AA 287-314) (ABIN3029872)

Target: ADA (Adenosine Deaminase (ADA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 608CT2-1-3

Product Details anti-ADA Antibody

Binding Specificity: AA 287-314

Purpose: ADA Antibody

Purification: Protein G affinity

Immunogen: A portion of amino acids 287-314 from the human protein was used as the immunogen for this ADA antibody.

Isotype: IgG1

Application Details

Application Notes: Titration of the ADA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ADA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ADA

Target: ADA (Adenosine Deaminase (ADA))

Alternative Name: ADA

Background: This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.

UniProt: P00813

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process