ADA antibody (AA 287-314)

Catalog No. ABIN3029870

The Rabbit Polyclonal anti-ADA antibody is suitable to detect ADA in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for ADA antibody (AA 287-314) (ABIN3029870)

Target: ADA (Adenosine Deaminase (ADA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADA antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ADA Antibody

Binding Specificity: AA 287-314

Purpose: ADA Antibody

Purification: Antigen affinity

Immunogen: A portion of amino acids 287-314 from the human protein was used as the immunogen for this ADA antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the ADA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ADA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ADA

Target: ADA (Adenosine Deaminase (ADA))

Alternative Name: ADA

Background: Adenosine deaminase (ADA) catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion. [UniProt]

UniProt: P00813

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process