AMPK alpha antibody

Catalog No. ABIN3032659

This Mouse Monoclonal antibody specifically detects AMPK alpha in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for AMPK alpha antibody (ABIN3032659)

Target: AMPK alpha (SNF1A) (SNF1A/AMP-Activated Protein Kinase (SNF1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AMPK alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 167CT22-1-6

Product Details anti-AMPK alpha Antibody

Cross-Reactivity (Details): Expected species reactivity: Rat

Purification: Purified

Immunogen: This AMPK alpha antibody was produced from a mouse immunized with PRKAA1 recombinant protein.

Isotype: IgG1 kappa

Application Details

Application Notes: Titration of the AMPK alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the AMPK alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for AMPK alpha

Target: AMPK alpha (SNF1A) (SNF1A/AMP-Activated Protein Kinase (SNF1A))

Alternative Name: AMPK alpha

Background: AMPK alpha is the catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. [UniProt]

UniProt: Q13131

Pathways: Warburg Effect