AMPK alpha antibody

Catalog No. ABIN3032659

Product Details anti-AMPK alpha Antibody

Target: AMPK alpha (SNF1A) (SNF1A/AMP-Activated Protein Kinase (SNF1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AMPK alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): Expected species reactivity: Rat

Purification: Purified

Immunogen: This AMPK alpha antibody was produced from a mouse immunized with PRKAA1 recombinant protein.

Clone: 167CT22-1-6

Isotype: IgG1 kappa

Application Details

Application Notes: Titration of the AMPK alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the AMPK alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for AMPK alpha

Target: AMPK alpha (SNF1A) (SNF1A/AMP-Activated Protein Kinase (SNF1A))

Alternative Name: AMPK alpha (SNF1A Products)

Synonyms: AMPK antibody, AMPK2 antibody, AMPKa2 antibody, PRKAA antibody, protein kinase AMP-activated catalytic subunit alpha 2 antibody, PRKAA2 antibody

Background: AMPK alpha is the catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. [UniProt]

UniProt: Q13131

Pathways: Warburg Effect