ANGPTL3 antibody (AA 82-114)

Catalog No. ABIN3029953

This Rabbit Polyclonal antibody specifically detects ANGPTL3 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for ANGPTL3 antibody (AA 82-114) (ABIN3029953)

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANGPTL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ANGPTL3 Antibody

Binding Specificity: AA 82-114

Purpose: ANGPTL3 Antibody / Angiopoietin-like protein 3

Purification: Purified

Immunogen: A portion of amino acids 82-114 from the human protein was used as the immunogen for this ANGPTL3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the ANGPTL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ANGPTL3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ANGPTL3

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Alternative Name: ANGPTL3

Background: ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.

UniProt: Q9Y5C1