ANGPTL4 antibody (AA 138-167)

Catalog No. ABIN3029955

This anti-ANGPTL4 antibody is a Rabbit Polyclonal antibody detecting ANGPTL4 in WB, IHC, ELISA and FACS. Suitable for Human and Mouse.

Quick Overview for ANGPTL4 antibody (AA 138-167) (ABIN3029955)

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANGPTL4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-ANGPTL4 Antibody

Binding Specificity: AA 138-167

Purification: Purified

Immunogen: A portion of amino acids 138-167 from the human protein was used as the immunogen for this ANGPTL4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the ANGPTL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ANGPTL4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ANGPTL4

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Alternative Name: ANGPTL4

Background: ANGPTL4 is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This protein is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes.

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha