Insulin antibody (AA 35-64)
Quick Overview for Insulin antibody (AA 35-64) (ABIN3028737)
Target
See all Insulin (INS) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 35-64
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Purification
- Purified
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Immunogen
- A portion of amino acids 35-64 from the human protein was used as the immunogen for this anti-Insulin antibody.
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Isotype
- IgM
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Application Notes
- Titration of the anti-Insulin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the anti-Insulin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Insulin (INS)
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Alternative Name
- Insulin
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Background
- Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. [UniProt]
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UniProt
- P01308
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Pathways
- NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Target
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