SIRT1 antibody (AA 587-621)

Catalog No. ABIN3029010

This anti-SIRT1 antibody is a Rabbit Polyclonal antibody detecting SIRT1 in WB and ELISA. Suitable for Human.

Quick Overview for SIRT1 antibody (AA 587-621) (ABIN3029010)

Target: SIRT1 (Sirtuin 1 (SIRT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SIRT1 Antibody

Binding Specificity: AA 587-621

Purification: Antigen affinity purified

Immunogen: This anti-SIRT1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 587-621 amino acids from the C-terminal region of human SIRT1.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the anti-SIRT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the anti-SIRT1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for SIRT1

Target: SIRT1 (Sirtuin 1 (SIRT1))

Alternative Name: SIRT1

Background: A NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy.

UniProt: Q96EB6

Pathways: MAPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling