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Aurora Kinase C antibody (AA 1-30)

This anti-Aurora Kinase C antibody is a Rabbit Polyclonal antibody detecting Aurora Kinase C in WB and ELISA. Suitable for Human.
Catalog No. ABIN3030081

Quick Overview for Aurora Kinase C antibody (AA 1-30) (ABIN3030081)

Target

See all Aurora Kinase C (AURKC) Antibodies
Aurora Kinase C (AURKC)

Reactivity

  • 68
  • 30
  • 18
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 68
  • 4
  • 1
Rabbit

Clonality

  • 71
  • 2
Polyclonal

Conjugate

  • 39
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aurora Kinase C antibody is un-conjugated

Application

  • 60
  • 30
  • 21
  • 16
  • 15
  • 5
  • 3
  • 1
Western Blotting (WB), ELISA
  • Binding Specificity

    • 9
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    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    AA 1-30

    Purification

    Purified

    Immunogen

    A portion of amino acids 1-30 from the human protein was used as the immunogen for this Aurora-C antibody.

    Isotype

    Ig Fraction
  • Application Notes

    Titration of the Aurora-C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Aliquot the Aurora-C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    Aurora Kinase C (AURKC)

    Alternative Name

    Aurora-C

    Background

    Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

    UniProt

    Q9UQB9

    Pathways

    Cell Division Cycle, Maintenance of Protein Location
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