Caspase 6 antibody (AA 235-263)

Catalog No. ABIN3030311

The Rabbit Polyclonal anti-Caspase 6 antibody is suitable to detect Caspase 6 in samples from Human and Mouse. It has been validated for WB, IHC and ELISA.

Quick Overview for Caspase 6 antibody (AA 235-263) (ABIN3030311)

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Caspase 6 Antibody

Binding Specificity: AA 235-263

Cross-Reactivity (Details): Expected species reactivity: Rat, Bovine

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 235-263 from the human protein was used as the immunogen for this Caspase-6 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Caspase-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Caspase-6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Alternative Name: Caspase-6

Background: CASP6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.

UniProt: P55212

Pathways: Apoptosis, Caspase Cascade in Apoptosis