Caspase 6 antibody (AA 17-45)

Catalog No. ABIN3030312

Product Details anti-Caspase 6 Antibody

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Binding Specificity: AA 17-45

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 17-45 from the human protein was used as the immunogen for this Caspase-6 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Caspase-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Caspase-6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Alternative Name: Caspase-6 (CASP6 Products)

Synonyms: xCaspase-6 antibody, mch2 antibody, caspase-6 antibody, zgc:112960 antibody, CASP6 antibody, casp6 antibody, Mch2 antibody, mCASP-6 antibody, MCH2 antibody, caspase 6 L homeolog antibody, caspase 6 antibody, caspase 6, apoptosis-related cysteine peptidase antibody, group XIIA secretory phospholipase A2 antibody, caspase-6 antibody, casp6.L antibody, casp6 antibody, CASP6 antibody, CpipJ_CPIJ017008 antibody, Casp6 antibody

Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq].

UniProt: P55212

Pathways: Apoptosis, Caspase Cascade in Apoptosis