Endoglin antibody (AA 380-409)
Quick Overview for Endoglin antibody (AA 380-409) (ABIN3030354)
Target
See all Endoglin (ENG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 380-409
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Purification
- Purified
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Immunogen
- A portion of amino acids 380-409 from the human protein was used as the immunogen for this CD105 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the CD105 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the CD105 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Endoglin (ENG)
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Alternative Name
- CD105
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Background
- CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in its gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
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UniProt
- P17813
Target
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