CD1c antibody (AA 226-253)

Catalog No. ABIN3030368

The Rabbit Polyclonal anti-CD1c antibody is suitable to detect CD1c in samples from Human. It has been validated for WB and ELISA.

Quick Overview for CD1c antibody (AA 226-253) (ABIN3030368)

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1c antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD1c Antibody

Binding Specificity: AA 226-253

Purpose: CD1c Antibody

Purification: Antigen affinity

Immunogen: A portion of amino acids 226-253 from the human protein was used as the immunogen for this CD1c antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CD1c antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CD1c antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD1c

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Alternative Name: CD1c

Background: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

UniProt: P29017