CHEK1 antibody

Catalog No. ABIN3028565

The Mouse Monoclonal anti-CHEK1 antibody has been validated for WB and ELISA. It is suitable to detect CHEK1 in samples from Human and Mouse.

Quick Overview for CHEK1 antibody (ABIN3028565)

Target: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CHEK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2G1D5

Product Details anti-CHEK1 Antibody

Purification: Purified

Immunogen: This monoclonal CHK1 antibody was produced from mice immunized with purified recombinant protein.

Isotype: IgM

Application Details

Application Notes: Titration of the CHK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1,000-1:4,000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CHK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CHEK1

Target: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Alternative Name: CHK1

Background: CHK1 is a serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. [UniProt]

UniProt: O14757

Pathways: p53 Signaling, Apoptosis, Cell Division Cycle, DNA Damage Repair