CYP1A1 antibody (AA 377-405)

Catalog No. ABIN3030670

This Rabbit Polyclonal antibody specifically detects CYP1A1 in WB, ELISA and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for CYP1A1 antibody (AA 377-405) (ABIN3030670)

Target: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP1A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CYP1A1 Antibody

Binding Specificity: AA 377-405

Cross-Reactivity (Details): Expected species reactivity: Primate

Purification: Purified

Immunogen: A portion of amino acids 377-405 from the human protein was used as the immunogen for this CYP1A1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CYP1A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CYP1A1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CYP1A1

Target: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Alternative Name: CYP1A1

Background: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, CYP1A1 is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. [UniProt]

UniProt: P04798

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha