DNMT3A antibody (AA 872-900)

Catalog No. ABIN3030747

This anti-DNMT3A antibody is a Rabbit Polyclonal antibody detecting DNMT3A in WB and ELISA. Suitable for Human.

Quick Overview for DNMT3A antibody (AA 872-900) (ABIN3030747)

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNMT3A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DNMT3A Antibody

Binding Specificity: AA 872-900

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Chicken

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 872-900 from the human protein was used as the immunogen for this Dnmt3a antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Dnmt3a antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Dnmt3a antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for DNMT3A

Target: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Alternative Name: Dnmt3a

Background: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

UniProt: Q9Y6K1