DNMT3A antibody (AA 872-900)
Quick Overview for DNMT3A antibody (AA 872-900) (ABIN3030747)
Target
See all DNMT3A AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 872-900
-
Purpose
- Dnmt3a Antibody
-
Cross-Reactivity (Details)
- Expected species reactivity: Mouse, Rat, Chicken
-
Purification
- Antigen affinity
-
Immunogen
- A portion of amino acids 872-900 from the human protein was used as the immunogen for this Dnmt3a antibody.
-
Isotype
- Ig Fraction
-
-
-
-
Application Notes
- Titration of the Dnmt3a antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Aliquot the Dnmt3a antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
-
Alternative Name
- Dnmt3a
-
Background
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
-
UniProt
- Q9Y6K1
Target
-