EPH Receptor B2 antibody

Catalog No. ABIN3030824

The Mouse Monoclonal anti-EPH Receptor B2 antibody has been validated for WB, ELISA, IHC and FACS. It is suitable to detect EPH Receptor B2 in samples from Human.

Quick Overview for EPH Receptor B2 antibody (ABIN3030824)

Target: EPH Receptor B2 (EPHB2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor B2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 48CT12-6-4

Product Details anti-EPH Receptor B2 Antibody

Purification: Purified

Immunogen: Purified His-tagged protein (from amino acids 127~425) was used to produce this monoclonal EPHB2 antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Titration of the EPHB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the EPHB2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for EPH Receptor B2

Target: EPH Receptor B2 (EPHB2)

Alternative Name: EPHB2

Background: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.

UniProt: P29323

Pathways: RTK Signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins