GAB1 antibody (AA 250-285)

Catalog No. ABIN3028685

The Rabbit Polyclonal anti-GAB1 antibody has been validated for WB and ELISA. It is suitable to detect GAB1 in samples from Human.

Quick Overview for GAB1 antibody (AA 250-285) (ABIN3028685)

Target: GAB1 (GRB2-Associated Binding Protein 1 (GAB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GAB1 Antibody

Binding Specificity: AA 250-285

Purification: Antigen affinity purified

Immunogen: This GAB1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 250-285 amino acids from human.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the GAB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the GAB1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for GAB1

Target: GAB1 (GRB2-Associated Binding Protein 1 (GAB1))

Alternative Name: GAB1

Background: Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).

UniProt: Q13480

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals