GATA4 antibody (AA 298-328)

Catalog No. ABIN3031033

This Rabbit Polyclonal antibody specifically detects GATA4 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for GATA4 antibody (AA 298-328) (ABIN3031033)

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-GATA4 Antibody

Binding Specificity: AA 298-328

Purpose: GATA4 Antibody

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Xenopus

Purification: Purified

Immunogen: A portion of amino acids 298-328 from the human protein was used as the immunogen for this GATA4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the GATA4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the GATA4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for GATA4

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Alternative Name: GATA4

Background: GATA4 is a transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development. [UniProt]

UniProt: P43694

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis