GSK3 beta antibody (AA 4-34)
Quick Overview for GSK3 beta antibody (AA 4-34) (ABIN3031095)
Target
See all GSK3 beta (GSK3b) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 4-34
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Cross-Reactivity (Details)
- Expected species reactivity: Mouse, Rat
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 4-34 from the human protein was used as the immunogen for this GSK3B antibody.
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Isotype
- Ig Fraction
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anti-Glycogen Synthase Kinase 3 beta (GSK3b) (N-Term) antibody
GSK3b Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) antibodyGSK3b Reactivity: Human, Mouse WB, IF, IP Host: Mouse Monoclonal 2E6-D6-C12 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 4-34), (N-Term) antibodyGSK3b Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB03816 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 30-59) antibodyGSK3b Reactivity: Mouse WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 362-395) antibodyGSK3b Reactivity: Rat WB Host: Rabbit Polyclonal RB56577 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 2-33) antibodyGSK3b Reactivity: Human, Rat WB Host: Rabbit Polyclonal RB56641 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 2-33), (pSer9) antibodyGSK3b Reactivity: Human WB Host: Rabbit Polyclonal RB56641 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) antibodyGSK3b Reactivity: Human, Mouse, Rat WB, IF, IP, ICC Host: Mouse Monoclonal 2E6-D6-C12 unconjugated
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Application Notes
- Titration of the GSK3B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the GSK3B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
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Alternative Name
- GSK3B
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Background
- GSK3B is a constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. May also mediate the development of insulin resistance by regulating activation of transcription factors. [UniProt]
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UniProt
- P49841
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Pathways
- WNT Signaling, Hedgehog Signaling, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, Warburg Effect
Target
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