High Mobility Group B Protein 4 (HMGB4) (AA 45-73) antibody

Catalog No. ABIN3031203

The Rabbit Polyclonal anti-High Mobility Group B Protein 4 antibody (ABIN3031203) specifically detects High Mobility Group B Protein 4 in WB and ELISA. The antibody is reactive with Human and Rat samples.

Quick Overview for High Mobility Group B Protein 4 (HMGB4) (AA 45-73) antibody (ABIN3031203)

Target: High Mobility Group B Protein 4 (HMGB4)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Product Details

Binding Specificity: AA 45-73

Cross-Reactivity (Details): Expected species reactivity: Bovine

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 45-73 from the human protein was used as the immunogen for this HMGB4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the HMGB4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HMGB4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details

Target: High Mobility Group B Protein 4 (HMGB4)

Alternative Name: HMGB4

Background: High Mobility Group (HMG) proteins, a group of chromosomal proteins common to all eukaryotes, bind DNA in a non-sequence-specific fashion to promote chromatin function and gene regulation, helping with transcription, replication, recombination, and DNA repair. HMGB4 is HMG2-like, isoform 2, high-mobility group box 4. This gene can be found on Chromosome 1. HMGB4 contains two HMG-box regions, and is found in a variety of eukaryotic chromosomal proteins. HMGB proteins are phosphorylated to various extents. The existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions.

UniProt: Q8WW32