IRAK2 antibody (AA 594-622)

Catalog No. ABIN3028765

Product Details anti-IRAK2 Antibody

Target: IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))

Binding Specificity: AA 594-622

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRAK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 594-622 from the mouse protein was used as the immunogen for this Irak2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Irak2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Irak2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for IRAK2

Target: IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))

Alternative Name: Irak2 (IRAK2 Products)

Synonyms: IRAK-2 antibody, 6330415L08Rik antibody, AI649099 antibody, interleukin 1 receptor associated kinase 2 antibody, interleukin-1 receptor-associated kinase 2 antibody, IRAK2 antibody, Irak2 antibody

Background: Irak2 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization (By similarity).

UniProt: Q8CFA1

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades