IRAK3 antibody (AA 517-544)
Quick Overview for IRAK3 antibody (AA 517-544) (ABIN3028766)
Target
See all IRAK3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 517-544
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Purpose
- Irak3 Antibody
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 517-544 from the mouse protein was used as the immunogen for this Irak3 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the Irak3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles
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Storage
- -20 °C
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Storage Comment
- Aliquot the Irak3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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Alternative Name
- Irak3
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Background
- Irak3 inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
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UniProt
- Q8K4B2
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Pathways
- TLR Signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
Target
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