IRAK4 antibody (AA 25-52)

Catalog No. ABIN3031497

The Rabbit Polyclonal anti-IRAK4 antibody (ABIN3031497) specifically detects IRAK4 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for IRAK4 antibody (AA 25-52) (ABIN3031497)

Target: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRAK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IRAK4 Antibody

Binding Specificity: AA 25-52

Purpose: IRAK4 Antibody

Cross-Reactivity (Details): Expected species reactivity: Mouse, Bovine

Purification: Antigen affinity

Immunogen: A portion of amino acids 25-52 from the human protein was used as the immunogen for this IRAK4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the IRAK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the IRAK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for IRAK4

Target: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Alternative Name: IRAK4

Background: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9NWZ3

Pathways: NF-kappaB Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades