IRF1 antibody (AA 74-102)

Catalog No. ABIN3031412

The Rabbit Polyclonal anti-IRF1 antibody has been validated for WB and ELISA. It is suitable to detect IRF1 in samples from Human.

Quick Overview for IRF1 antibody (AA 74-102) (ABIN3031412)

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IRF1 Antibody

Binding Specificity: AA 74-102

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Bovine, Pig

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 74-102 from the human protein was used as the immunogen for this IRF-1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the IRF-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the IRF-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for IRF1

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Alternative Name: IRF-1

Background: IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

UniProt: P10914

Pathways: Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy