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JAK2 antibody (AA 666-694)

This anti-JAK2 antibody is a Rabbit Polyclonal antibody detecting JAK2 in WB, IHC and ELISA. Suitable for Mouse.
Catalog No. ABIN3031509

Quick Overview for JAK2 antibody (AA 666-694) (ABIN3031509)

Target

See all JAK2 Antibodies
JAK2 (Janus Kinase 2 (JAK2))

Reactivity

  • 153
  • 95
  • 90
  • 19
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  • 3
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  • 1
Mouse

Host

  • 163
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Rabbit

Clonality

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Polyclonal

Conjugate

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This JAK2 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Binding Specificity

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    AA 666-694

    Cross-Reactivity (Details)

    Expected species reactivity: Rat, Pig

    Purification

    Antigen affinity purified

    Immunogen

    A portion of amino acids 666-694 from the human protein was used as the immunogen for this JAK2 antibody.

    Isotype

    Ig Fraction
  • Application Notes

    Titration of the JAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Aliquot the JAK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    JAK2 (Janus Kinase 2 (JAK2))

    Alternative Name

    JAK2

    Background

    This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

    UniProt

    O60674

    Pathways

    JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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