KDM6A antibody (C-Term)

Catalog No. ABIN3031655

The Rabbit Polyclonal anti-KDM6A antibody has been validated for WB and ELISA. It is suitable to detect KDM6A in samples from Mouse.

Quick Overview for KDM6A antibody (C-Term) (ABIN3031655)

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM6A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KDM6A Antibody

Binding Specificity: C-Term

Purification: Antigen affinity purified

Immunogen: This mouse Kdm6a antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1041-1074 amino acids from the C-terminal region of mouse Kdm6a.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Kdm6a antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Kdm6a antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for KDM6A

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Alternative Name: Kdm6a

Background: Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (By similarity).

UniProt: O70546

Pathways: Tube Formation, Warburg Effect