Kdm6b antibody (AA 1023-1057)

Catalog No. ABIN3031658

Product Details anti-Kdm6b Antibody

Target: Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

Binding Specificity: AA 1023-1057

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kdm6b antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogen: This Kdm6b antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1023-1057 amino acids from mouse Kdm6b.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Kdm6b antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Kdm6b antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Kdm6b

Target: Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

Alternative Name: Kdm6b (Kdm6b Products)

Background: Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.

UniProt: Q5NCY0

Pathways: Warburg Effect