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LCK antibody (AA 23-52)

The Rabbit Polyclonal anti-LCK antibody (ABIN3031644) specifically detects LCK in WB, ELISA, IHC, IF and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Confocal immunofluorescent analysis of LCK antibody with A2058 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (LCK antibody (AA 23-52))

IHC analysis of FFPE human breast carcinoma tissue stained with the LCK antibody (LCK antibody (AA 23-52))

IHC

LCK antibody flow cytometric analysis of A2058 cells (green) compared to a negative control (blue). (LCK antibody (AA 23-52))

FACS

6 images

Catalog No. ABIN3031644

$612.54

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Quick Overview for LCK antibody (AA 23-52) (ABIN3031644)

Target

See all LCK Antibodies

LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

Reactivity

Human, Mouse, Rat

Host

Rabbit

Clonality

Polyclonal

Conjugate

This LCK antibody is un-conjugated

Application

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Discover our top product LCK Primary Antibody

Binding Specificity
29

16

16

10

8

8

7

7

6

4

4

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 23-52

Purpose

LCK Antibody

Purification

Antigen affinity

Immunogen

A portion of amino acids 23-52 from the human protein was used as the immunogen for this LCK antibody.

Isotype

Ig Fraction
anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-240) antibody
LCK Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK Reactivity: Human WB, ELISA, IP, RNAi Host: Mouse Monoclonal 3F7-F5 unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 22-36) antibody
LCK Reactivity: Human WB, IP, ICC, ICFC Host: Mouse Monoclonal LCK-01 unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK Reactivity: Human ELISA, IHC, IF, IP Host: Rabbit Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 23-52), (N-Term) antibody
LCK Reactivity: Human, Mouse WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB3088 unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (C-Term) antibody
LCK Reactivity: Human, Mouse, Rat WB, IHC, IF, FACS, ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 39-52) antibody
Verified LCK Reactivity: Human, Rat, Pig WB, ELISA Host: Goat Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (pTyr505) antibody
LCK Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 480-509), (C-Term) antibody
LCK Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB17753 unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 421-509) antibody
LCK Reactivity: Human WB, FACS Host: Rabbit Polyclonal unconjugated

Application Notes

Titration of the LCK antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions

For Research Use only
Format

Liquid

Buffer

In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeated freeze-thaw cycles

Storage

-20 °C

Storage Comment

Aliquot the LCK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target

LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

Alternative Name

LCK

Background

LCK, which belongs to the SRC subfamily of Tyr protein kinases, may participate in antigen-induced T-cell activation. It binds to phosphatidylinositol 3'-kinase (PI3K) from T lymphocytes through its SH3 domain and to the tyrosine phosphorylated form of KHDRBS1/p70 through its SH2 domain. LCK is bound to the cytoplasmic domain of either CD4 or CD8. This protein is involved in leukemias by a chromosomal translocation t(1,7)(p34,q34) which involves LCK and T-cell receptor beta chain (TCRB) genes.

UniProt

P06239

Pathways

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling