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Leptin Receptor antibody (AA 23-52)

LEPR Reactivity: Human FACS, IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031603
$578.58
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  • Target See all Leptin Receptor (LEPR) Antibodies
    Leptin Receptor (LEPR)
    Binding Specificity
    • 19
    • 17
    • 13
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-52
    Reactivity
    • 127
    • 77
    • 51
    • 20
    • 5
    • 4
    • 2
    Human
    Host
    • 110
    • 19
    • 9
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 117
    • 24
    Polyclonal
    Conjugate
    • 54
    • 12
    • 9
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Leptin Receptor antibody is un-conjugated
    Application
    • 68
    • 59
    • 35
    • 27
    • 27
    • 27
    • 14
    • 12
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Purification
    Purified
    Immunogen
    A portion of amino acids 23-52 from the human protein was used as the immunogen for this Leptin Receptor antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the Leptin Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the Leptin Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    Leptin Receptor (LEPR)
    Alternative Name
    Leptin Receptor (LEPR Products)
    Synonyms
    CD295 antibody, LEP-R antibody, LEPRD antibody, OB-R antibody, OBR antibody, obr antibody, cd295 antibody, ob-rb antibody, Fa antibody, LEPROT antibody, Leprb antibody, Modb1 antibody, OB-RGRP antibody, Obr antibody, db antibody, diabetes antibody, obese-like antibody, obl antibody, ObRb antibody, Ob-R antibody, Ob-RM antibody, lepr antibody, leptin receptor antibody, leptin receptor S homeolog antibody, LEPR antibody, lepr antibody, Lepr antibody, lepr.S antibody
    Background
    Leptin, an adipocyte-specific hormone, regulates adipose-tissue mass through hypothalamic effects on satiety and energy expenditure by acting through the leptin receptor (LEPR). LEPR is a single-transmembrane-domain receptor of the cytokine receptor family that is identical to the mouse diabetes (db) gene product. During weight loss, leptin levels decrease, whereas soluble LEPR levels and the receptor bound fraction of leptin increases. The presence of LEPR in the absorptive cells of the small intestine suggests that leptin may have a physiological role in the regulation of nutrient absorption.
    UniProt
    P48357
    Pathways
    JAK-STAT Signaling, AMPK Signaling, Feeding Behaviour
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