LOX antibody (AA 234-260)

Catalog No. ABIN3031667

The Mouse Monoclonal anti-LOX antibody has been validated for WB and ELISA. It is suitable to detect LOX in samples from Human.

Quick Overview for LOX antibody (AA 234-260) (ABIN3031667)

Target: LOX (Lysyl Oxidase (LOX))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LOX antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 624CT23-7-3

Product Details anti-LOX Antibody

Binding Specificity: AA 234-260

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Pig

Purification: Purified

Immunogen: A portion of amino acids 234-260 from the human protein was used as the immunogen for this LOX antibody.

Isotype: IgG2b

Application Details

Application Notes: Titration of the LOX antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the LOX antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for LOX

Target: LOX (Lysyl Oxidase (LOX))

Alternative Name: LOX

Background: The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P28300

Pathways: SARS-CoV-2 Protein Interactome