MCM7 antibody (AA 290-318)
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- Target See all MCM7 Antibodies
- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
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Binding Specificity
- AA 290-318
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MCM7 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 290-318 from the human protein was used as the immunogen for this MCM7 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MCM7 Primary Antibody
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anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 1-389) antibody
MCM7 Reactivity: Human WB, IF, IHC (p), ELISA, PLA Host: Mouse Monoclonal 6C2 unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) antibodyMCM7 Reactivity: Human WB, IF, IHC (p), IP, ICC, ChIP Host: Rabbit Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 360-719) antibodyMCM7 Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 526-719) antibodyMCM7 Reactivity: Human, Mouse, Rat WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (Internal Region) antibodyMCM7 Reactivity: Human, Mouse, Rat WB, IHC (p), ELISA Host: Rabbit Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal MCM7-1466 unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 Reactivity: Human WB, IHC, StM Host: Rabbit Monoclonal MCM7-2832R unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 Reactivity: Human IHC, IF, FACS, StM Host: Mouse Monoclonal MCM7-1467 unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal rMCM7-1468 unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 1-719) antibodyMCM7 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Titration of the MCM7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the MCM7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
- Alternative Name
- MCM7 (MCM7 Products)
- Background
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
- UniProt
- P33993
- Pathways
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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