MITF antibody (AA 1-28)
Quick Overview for MITF antibody (AA 1-28) (ABIN3031775)
Target
See all MITF AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-28
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Purpose
- MITF Antibody
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Cross-Reactivity (Details)
- Expected species reactivity: Mouse
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 1-28 from the human protein was used as the immunogen for this MITF antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the MITF antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the MITF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MITF (Microphthalmia-Associated Transcription Factor (MITF))
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Alternative Name
- MITF
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Background
- This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
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UniProt
- O75030
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Pathways
- Chromatin Binding
Target
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