MSH2 antibody (AA 637-665)
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- Target See all MSH2 Antibodies
- MSH2 (Mismatch Repair Protein 2 (MSH2))
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Binding Specificity
- AA 637-665
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MSH2 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Western Blotting (WB)
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 637-665 from the human protein was used as the immunogen for this MSH2 antibody.
- Isotype
- Ig Fraction
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- Application Notes
- Titration of the MSH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the MSH2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- MSH2 (Mismatch Repair Protein 2 (MSH2))
- Alternative Name
- MSH2 (MSH2 Products)
- Synonyms
- COCA1 antibody, FCC1 antibody, HNPCC antibody, HNPCC1 antibody, LCFS2 antibody, AI788990 antibody, wu:fc06b02 antibody, wu:fc13e09 antibody, zgc:55333 antibody, msh2 antibody, mutS homolog 2 antibody, mutS homolog 2 (E. coli) antibody, mutS homolog 2 L homeolog antibody, MutS protein homolog 2 antibody, MSH2 antibody, Msh2 antibody, msh2 antibody, msh2.L antibody
- Background
- MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq].
- UniProt
- P43246
- Pathways
- DNA Damage Repair, Production of Molecular Mediator of Immune Response