MUC1 antibody (N-Term)

Catalog No. ABIN3031867

This Mouse Monoclonal antibody specifically detects MUC1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for MUC1 antibody (N-Term) (ABIN3031867)

Target: MUC1 (Mucin 1 (MUC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 347CT26-1-3

Product Details anti-MUC1 Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: Purified His-tagged N-terminal protein fragment was used to produced this monoclonal MUC1 antibody.

Isotype: IgG2b

Application Details

Application Notes: Titration of the MUC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MUC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for MUC1

Target: MUC1 (Mucin 1 (MUC1))

Alternative Name: MUC1

Background: This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq].

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling