MUC1 antibody (AA 1202-1231)

Catalog No. ABIN3031860

The Rabbit Polyclonal anti-MUC1 antibody (ABIN3031860) specifically detects MUC1 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for MUC1 antibody (AA 1202-1231) (ABIN3031860)

Target: MUC1 (Mucin 1 (MUC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MUC1 Antibody

Binding Specificity: AA 1202-1231

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 1202-1231 from the human protein was used as the immunogen for this MUC1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the MUC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MUC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for MUC1

Target: MUC1 (Mucin 1 (MUC1))

Alternative Name: MUC1

Background: The MUC1 alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity. [UniProt]

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling