NEU1 antibody (AA 188-214)

Catalog No. ABIN3032558

The Rabbit Polyclonal anti-NEU1 antibody is suitable to detect NEU1 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for NEU1 antibody (AA 188-214) (ABIN3032558)

Target: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEU1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NEU1 Antibody

Binding Specificity: AA 188-214

Purpose: NEU1 Antibody / Sialidase-1

Cross-Reactivity (Details): Expected species reactivity: Bovine

Purification: Antigen affinity

Immunogen: A portion of amino acids 188-214 from the human protein was used as the immunogen for this NEU1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the NEU1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NEU1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for NEU1

Target: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Alternative Name: NEU1

Background: The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.

UniProt: Q99519

Pathways: SARS-CoV-2 Protein Interactome