OXT antibody (AA 11-40)

Catalog No. ABIN3032559

This anti-OXT antibody is a Rabbit Polyclonal antibody detecting OXT in WB, ELISA, IHC and FACS. Suitable for Human.

Quick Overview for OXT antibody (AA 11-40) (ABIN3032559)

Target: OXT (Oxytocin, Prepropeptide (OXT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OXT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-OXT Antibody

Binding Specificity: AA 11-40

Purification: Purified

Immunogen: A portion of amino acids 11-40 from the human protein was used as the immunogen for this NEU1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the NEU1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NEU1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for OXT

Target: OXT (Oxytocin, Prepropeptide (OXT))

Alternative Name: Oxytocin-neurophysin 1

Background: There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.

UniProt: P01178

Pathways: Myometrial Relaxation and Contraction, Feeding Behaviour