NK2 Homeobox 5 antibody (AA 2-5)

Catalog No. ABIN3032008

Product Details anti-NK2 Homeobox 5 Antibody

Target: NK2 Homeobox 5 (NKX2-5)

Binding Specificity: AA 2-5

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NK2 Homeobox 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 2-5 from the human protein was used as the immunogen for this NKX2.5 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the NKX2.5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NKX2.5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for NK2 Homeobox 5

Target: NK2 Homeobox 5 (NKX2-5)

Alternative Name: NKX2.5 (NKX2-5 Products)

Synonyms: CHNG5 antibody, CSX antibody, CSX1 antibody, HLHS2 antibody, NKX2.5 antibody, NKX2E antibody, NKX4-1 antibody, VSD3 antibody, Csx antibody, Nkx-2.5 antibody, Nkx2.5 antibody, tinman antibody, nk2.5 antibody, nkx2-5 antibody, zgc:111912 antibody, AR2 antibody, XNkx2-5 antibody, csx antibody, nkx-2.5 antibody, nkx2-5b antibody, nkx2.5 antibody, NKX2-5 antibody, Nkx2-5 antibody, csx1 antibody, nkx2e antibody, XNkx-2.5 antibody, CNKX-2.5 antibody, NKX-2.5 antibody, NK2 homeobox 5 antibody, NK2 homeobox 5 S homeolog antibody, NKX2-5 antibody, Nkx2-5 antibody, nkx2.5 antibody, nkx2-5.S antibody, nkx2-5 antibody

Background: This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

UniProt: P52952

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development