NLRP12 antibody (AA 183-212)

Catalog No. ABIN3032015

Product Details anti-NLRP12 Antibody

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Binding Specificity: AA 183-212

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 183-212 from the human protein was used as the immunogen for this NLRP12 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the NLRP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NLRP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for NLRP12

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Alternative Name: NLRP12 (NLRP12 Products)

Synonyms: Nalp12 antibody, NALP12 antibody, CLR19.3 antibody, FCAS2 antibody, PAN6 antibody, PYPAF7 antibody, RNO antibody, RNO2 antibody, NLR family, pyrin domain containing 12 antibody, NLR family pyrin domain containing 12 antibody, NACHT, LRR and PYD domains-containing protein 3 antibody, Nlrp12 antibody, NLRP12 antibody, LOC100018508 antibody

Background: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome