NLRP12 antibody (AA 183-212)
Quick Overview for NLRP12 antibody (AA 183-212) (ABIN3032015)
Target
See all NLRP12 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 183-212
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Purpose
- NLRP12 Antibody
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 183-212 from the human protein was used as the immunogen for this NLRP12 antibody.
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Isotype
- Ig Fraction
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anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 183-212), (N-Term) antibody
NLRP12 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB33963 unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 1-110) antibodyNLRP12 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4B9 unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) antibodyNLRP12 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (Internal Region) antibodyVerified NLRP12 Reactivity: Mouse WB, ELISA Host: Goat Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 862-1062) antibodyNLRP12 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) antibodyNLRP12 Reactivity: Mouse WB, ELISA Host: Mouse Monoclonal 228CT4-1-3 unconjugated
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Application Notes
- Titration of the NLRP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the NLRP12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
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Alternative Name
- NLRP12
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Background
- This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
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UniProt
- P59046
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Pathways
- Positive Regulation of Endopeptidase Activity, Inflammasome
Target
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