×
For best experience we recommend to activate Javascript in your browser.
NOTCH3 antibody (AA 2291-2321)
NOTCH3
Reactivity: Human
ELISA, WB
Host: Mouse
Monoclonal
487CT6-9-2
unconjugated
Catalog No. ABIN3032031
$578.58
Plus shipping costs $45.00
0.08 mL ABIN4954751
0.4 mL ABIN3032031
0.08 mL ABIN4954751
0.4 mL ABIN3032031
Delivery in 2 to 3 Business Days
Product Details anti-NOTCH3 Antibody
(hide)
Target
See all NOTCH3 Antibodies
NOTCH3
(Notch 3 (NOTCH3))
Binding Specificity
All epitopes for NOTCH3 antibodies
AA 2291-2321
Reactivity
All reactivities for NOTCH3 antibodies
Human
Host
All hosts for NOTCH3 antibodies
Mouse
Clonality
All clonalities for NOTCH3 antibodies
Monoclonal
Conjugate
All conjugates for NOTCH3 antibodies
This NOTCH3 antibody is un-conjugated
Application
All applications for NOTCH3 antibodies
ELISA, Western Blotting (WB)
Purification
Purified
Immunogen
A portion of amino acids 2291-2321 from the human protein was used as the immunogen for this NOTCH3 antibody.
Clone
487CT6-9-2
Isotype
IgG1
Alternatives
(show)
Application Details
(hide)
Application Notes
Titration of the NOTCH3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the NOTCH3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target Details for NOTCH3
(hide)
Target
NOTCH3
(Notch 3 (NOTCH3))
Alternative Name
NOTCH3 (NOTCH3 Products )
Synonyms
CADASIL antibody, CASIL antibody, IMF2 antibody, AW229011 antibody, N3 antibody, hpbk antibody, fa14b08 antibody, notch5 antibody, wu:fa14b08 antibody, notch 3 antibody, NOTCH3 antibody, Notch3 antibody, notch3 antibody
Background
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq].
UniProt
Q9UM47
Pathways
Notch Signaling