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NOTCH3 antibody (AA 2291-2321)

NOTCH3 Reactivity: Human ELISA, WB Host: Mouse Monoclonal 487CT6-9-2 unconjugated
Catalog No. ABIN3032031
$578.58
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  • Target See all NOTCH3 Antibodies
    NOTCH3 (Notch 3 (NOTCH3))
    Binding Specificity
    • 5
    • 3
    • 3
    • 1
    AA 2291-2321
    Reactivity
    • 14
    • 7
    • 4
    • 1
    Human
    Host
    • 12
    • 3
    • 1
    Mouse
    Clonality
    • 12
    • 4
    Monoclonal
    Conjugate
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    This NOTCH3 antibody is un-conjugated
    Application
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Purification
    Purified
    Immunogen
    A portion of amino acids 2291-2321 from the human protein was used as the immunogen for this NOTCH3 antibody.
    Clone
    487CT6-9-2
    Isotype
    IgG1
  • Application Notes
    Titration of the NOTCH3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the NOTCH3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    NOTCH3 (Notch 3 (NOTCH3))
    Alternative Name
    NOTCH3 (NOTCH3 Products)
    Synonyms
    CADASIL antibody, CASIL antibody, IMF2 antibody, AW229011 antibody, N3 antibody, hpbk antibody, fa14b08 antibody, notch5 antibody, wu:fa14b08 antibody, notch 3 antibody, NOTCH3 antibody, Notch3 antibody, notch3 antibody
    Background
    This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq].
    UniProt
    Q9UM47
    Pathways
    Notch Signaling
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